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Establishing an automated high-throughput assay that supports the growth of prostate cancer organoids
Researchers concluded that their study demonstrates the ability to automate preclinical testing with prostate cancer organoids with diverse phenotypes.
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Assessing nanomedicine delivery across the blood-brain barrier using pre-clinical in vivo imaging
Researchers discuss the rationalrationale behind utilizing various pre-clinical in vivo imaging techniques to explore the uptake of custom-designed nanomedicines at different stages of brain cancer.
Publication Icon   Literature - Publication Review
Next-generation antimalarials: new hope on the horizon
In this literature review, we explore the emerging challenge of antimalarial drug resistance and the need to analyze all stages of the malaria parasite lifecycle to help develop the next generation of therapeutics.
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Research spotlight: new therapeutic targets focusing on aberrant lipid metabolism in Alzheimer’s disease
This whitepaper explores new therapeutic targets focusing on Aberrant Lipid Metabolism in Alzheimer's Disease
Whitepaper Icon   Whitepaper
Dual NIR imaging of β-Amyloid plaques and Tau tangles provides potential insights into Alzheimer’s disease
The use of Dual NIR Imaging of β-Amyloid Plaques and Tau Tangles to provide Potential Insights into Alzheimer’s Disease
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Bioluminescence Resonance Energy Transfer (BRET) to monitor protein-protein interactions
The ability to image PPIs in vivo has important implications for a wide variety of biological research endeavors, including drug discovery and molecular medicine.
Case Study Icon   Case Study
A novel non-Invasive in vivo tool for the assessment of NASH
Visualizing and quantifying NASH in a preclinical in vivo imaging model using the IVIS Lumina Series III optical and Quantum GX2 microCT imaging systems.
Case Study Icon   Case Study
Optical and microCT imaging enables noninvasive monitoring of EBV-induced neuroinvasion
Researchers use optical and microCT imaging to noninvasively monitor EBV-induced neuroinvasion in a mouse model.
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Non-invasive optical imaging for viral research and novel therapeutic and vaccine development
Non-invasive optical image using IVIS ® systems for pre-clinical viral research.
Publication Icon   Literature - Publication Review
Exploring mechanisms behind alphavirus-induced post-encephalitic parkinsonism
neuroinvasive viruses eliciting neurodegenerative symptoms of post-encephalitic parkinsonism by using bioluminescent or fluorescent recombinant WEEV in an in vivo mouse model
Publication Icon   Literature - Publication Review
Utility of engineered human Neural Stem Cells (NSCs) expressing varying exon 1 HTT fragments to study Huntington’s disease
Huntington's disease is most commonly caused by an expansion mutation in the CAG trinucleotide repeat within exon 1 of the HTT gene which codes for the protein huntingtin.
Publication Icon   Literature - Publication Review
Countering vascular calcification through mitochondrial phosphate transport inhibition in a CKD murine model
Researcher using in vivo imaging to study countering vascular calcification through mitochondrial phosphate transport inhibition in chronic kidney disease.
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