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Application Note Icon   Application Note
TCR phospho signaling investigation with HTRF
In this Note, we used HTRF phospho assays to study specific and ubiquitous proteins in the TCR pathway (ZAP70, SLP76, ERK …) in Peripheral Blood Mononuclear Cells (PBMC) and isolated T cells both under stimulation and in checkpoint inhibition conditions.
Guide Icon   Guide
The ultimate guide: key guidelines to successful cell signaling experiments
Cell signaling, guide to optimizing your phospho-/total protein assays
Whitepaper Icon   Whitepaper
Eyes on synaptotagmin 7 (SYT7) in synaptic function and neuroplastic health for cognitive decline
Researcher, Dr. Jason Vevea, describes the role of synaptotogmin 7 in the synaptic vesicle cycle and the experimental steps taken to discover that SYT7 supports asynchronous release, short-term synaptic plasticity, and synaptic vesicle replenishment.
Guide Icon   Guide
AlphaLISA SureFire Ultra: the ultimate guide for successful experiments
The definitive guide for setting up a successful AlphaLISA SureFire Ultra assay. Several biological processes are regulated by protein phosphorylation.
Brochure Icon   Brochure
CF-220 centrifuge brochure
CF-220 centrifuge brochure
Application Note Icon   Application Note
Simple and sensitive HTRF mutant and total HTT immunoassays to speed up the discovery of new drugs against Huntington’s disease
This application note demonstrates how the HTRF® soluble Mutant and Total HTT immunoassays are suitable for a sensitive and reliable measurement of HTT proteins in cell and brain tissue lysates.
eBook Icon   eBook
Autophagy regulation eBook
Key facts about autophagy and mitophagy; Infographics to apprehend the basics; Cutting-edge knowledge. Download this eBook.
Application Note Icon   Application Note
Quantifying the degradation of RBM39 in Neuroblastoma cells treated with molecular glue degraders using HTRF technology
This application note highlights the use of HTRF immunoassays to evaluate RBM39 degradation in neuroblastoma cancer cells treated with Indilsulam and CeMM1-4 molecular glue degraders.
Flyer Icon   Flyer
Simplify your 16S library prep and analysis.
This flyer provides guidance on which NEXTFLEX metagenomic kit to use for microbial community profiling projects
Whitepaper Icon   Whitepaper
An overview of atherosclerosis
Recent developments in our understanding of atherosclerosis from a molecular perspective include the discovery of new players in disease pathogenesis. Discover more in this white paper!
Application Note Icon   Application Note
Investigate mechanism of action of drugs targeting TDP-43 phosphorylation and aggregation with HTRF-based detection assays
This Application Note Illustrates how to assess phospho-TDP-43 modulation (Ser 409/410) with HTRF assays combined to the Protein Disaggregation kit in aggregated models.
Application Note Icon   Application Note
Homogenization of hemp and cannabis flowers using the Omni Bead Ruptor 96 well plate homogenizer
Streamlined and optimized cannabinoid analysis using bead mill homogenization as sample prep for HPLC-UV analysis
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