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Application Note Icon   Application Note
Imaging bile canaliculi in 3D liver microtissues
Here, we describe a 3D HCS assay to study hepatobiliary transporter function in InSphero human liver microtissues using the Opera Phenix™ HCS system.
Publication Icon   Literature - Publication Review
Developing a phenotypic in vitro model for progression of liver steatosis
A recent study developed a model of hepatic steatosis in functional human induced pluripotent stem cell-derived hepatocytes (hiPSC-Hep).
Case Study Icon   Case Study
A workflow to characterize and benchmark human induced pluripotent stem cells
Case study describing a high-content imaging workflow to characterize and benchmark human induced pluripotent stem cells
Technical Note Icon   Technical Note
How to perform successful long term live cell imaging in a high-content analysis system
How to perform successful long term live cell imaging in a high-content analysis system
Publication Icon   Literature - Publication Review
Artemisinins target GABAA receptor signaling and impair α cell identity
Artemisinins Target GABA Receptor Signaling and Impair α Cell Identity encouraging α cells to convert into insulin-producing β-like cells.
Whitepaper Icon   Whitepaper
Spotlight research interview: narcolepsy, a neurological autoimmune disorder
Researchers were first to demonstrate direct evidence of autoreactive immune cells in narcolepsy patients, providing evidence of autoimmune basis
Guide Icon   Guide
ELISA to Alpha Immunoassay conversion guide
ELISA to Alpha Immunoassay conversion guide
Publication Icon   Literature - Publication Review
Inhibiting interleukin 11 signaling reduces and reverses many dangerous effects of NAFLD/NASH in mouse models
Study demonstrating that inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of NASH
Publication Icon   Literature - Publication Review
Bone morphogenetic protein 8B - a promising therapeutic avenue for NASH treatment
Bone Morphogenetic Protein 8B investigated as a Promising Therapeutic Avenue for NASH Treatment
Publication Icon   Literature - Publication Review
Exploring mechanisms behind alphavirus-induced post-encephalitic parkinsonism
neuroinvasive viruses eliciting neurodegenerative symptoms of post-encephalitic parkinsonism by using bioluminescent or fluorescent recombinant WEEV in an in vivo mouse model
Publication Icon   Literature - Publication Review
Utility of engineered human Neural Stem Cells (NSCs) expressing varying exon 1 HTT fragments to study Huntington’s disease
Huntington's disease is most commonly caused by an expansion mutation in the CAG trinucleotide repeat within exon 1 of the HTT gene which codes for the protein huntingtin.
Publication Icon   Literature - Publication Review
Prolonging ß cell proliferation with a 3D culture system
Disque Platform technology for evaluating drug candidates to treat ß cell loss in patients with diabetes.
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