The next generation of automated DNA and RNA purification

The chemagic Prime instrument is your ultimate solution for high-throughput automated DNA and RNA purification. Combining chemagen’s patented M-PVA Magnetic Bead Technology with advanced liquid handling capabilities, this instrument ensures the fully automated isolation of ultra-pure, high-integrity nucleic acids from various sample types.

Key features

• Performance: Achieve high yields, integrity, and purity of nucleic acids, proven effective in long-read sequencing, NGS, PCR, MLPA, and more.
• Flexibility: Handle sample volumes up to 10 ml, process 1-192 samples per run, and accommodate diverse tubes/sample types in a single run. Perform downstream normalization, assay setup, and eluate transfer with ease.
• Automated traceability: Benefit from on-deck 1D/2D barcode scanning, LIMS-compatible log files, and customizable run reports.
• Quality assurance: Ensure 100% traceability, tracked reagent/tip consumption, safe travel paths, UV disinfection, and drop cover.
• Efficiency: Optimize reagent dispensing without expensive cartridges, use multiple kits with a switchbox, and enjoy on-deck heating/cooling/shaking options.
• Ease of operation: Experience user-friendly operation with status lights, fast start-up, intuitive software, guided setup and maintenance, and email notifications of errors.

chemagic Prime configuration

The chemagic Prime can be configured with two kinds of chemagic Rod Heads to process sample volumes from 50 μL - 10 mL.

Exemplary workflows with chemagic Prime

High-Throughput blood donor screening: Analyze up to 552 blood bags routinely with high traceability and sensitivity for detecting HIV, HCV, HBV, and malaria.¹

Genetic study of autism spectrum disorder: Isolate high-quality DNA from saliva samples for high-resolution SNP genotyping, crucial for identifying pathogenic mutations in children with autism.²

Pathogen surveillance: Detect SARS-CoV-2 from various samples, including blood, swabs, and wastewater, with high throughput and sensitivity.^3,4,5,6

chemagic Prime kits

Our kits are designed for the isolation of DNA and RNA from various specimens such as whole blood, saliva, and plasma. Each kit is ready-to-use with plastic consumables included and is based on well-established chemagic M-PVA Magnetic Bead and buffer chemistry.

Request a demo

Discover how the chemagic Prime instrument can revolutionize your laboratory workflows. Request a demo today and experience the future of automated nucleic acid purification.

1. Costa E, Rocha D, Lopes JIF, et al. Detection of Plasmodium spp. in asymptomatic blood donors by the new Brazilian NAT PLUS HIV/HBV/HCV/Malaria Bio-Manguinhos kit. Transfusion. 2024;64(3):501-509. doi:10.1111/trf.17726
2. Bui DT, Ton ANV, Nguyen CTD, et al. Pathogenic/likely pathogenic mutations identified in Vietnamese children diagnosed with autism spectrum disorder using high-resolution SNP genotyping platform. Sci Rep. 2024;14(1):2360. Published 2024 Jan 29. doi:10.1038/s41598-024-52777-y
3. Döhla M, Schulte B, Wilbring G, et al. SARS-CoV-2 in Environmental Samples of Quarantined Households. Viruses. 2022;14(5):1075. Published 2022 May 17. doi:10.3390/v14051075
4. Lou EG, Sapoval N, McCall C, et al. Direct comparison of RT-ddPCR and targeted amplicon sequencing for SARS-CoV-2 mutation monitoring in wastewater. Sci Total Environ. 2022;833:155059. doi:10.1016/j.scitotenv.2022.155059
5. Streeck H, Schulte B, Kümmerer BM, et al. Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany. Nat Commun. 2020;11(1):5829. Published 2020 Nov 17. doi:10.1038/s41467-020-19509-y
6. LaTurner ZW, Zong DM, Kalvapalle P, et al. Evaluating recovery, cost, and throughput of different concentration methods for SARS-CoV-2 wastewater-based epidemiology. Water Res. 2021;197:117043. doi:10.1016/j.watres.2021.117043