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Whitepaper

A guide to In Vitro Transcription (IVT) and the importance of dsRNA detection

In vitro transcription (IVT) is a key molecular biology technique that synthesizes RNA from a DNA template. This method is vital for applications such as RNA-based therapeutics, gene expression studies, and synthetic biology.

However, double-stranded RNA (dsRNA) contaminants can provoke immune responses, making their detection and removal crucial. This white paper delves into the IVT process, the significance of dsRNA detection, and advanced methods to ensure RNA product quality and safety.

The HTRF dsRNA (IVT) assay provides a robust solution for identifying dsRNA contaminants, supporting stringent QA/QC processes in biotherapeutic production. Discover more in this white paper.

For research use only. Not for use in diagnostic procedures.

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A guide to In Vitro Transcription (IVT) and the importance of dsRNA detection