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Guide Icon   Guide
The ultimate guide: key guidelines to successful cell signaling experiments
Cell signaling, guide to optimizing your phospho-/total protein assays
Technical Note Icon   Technical Note
Optimization and pharmacological validation of wild type beta-arrestin 2 plasmid transfection
This technical note provides details on how transfecting cell lines with a beta-arrestin plasmid can lead to an increase in beta-arrestin 2 recruitment signals and restoration of beta-arrestin 2 in otherwise deficient cells.
Application Note Icon   Application Note
Simple and sensitive HTRF mutant and total HTT immunoassays to speed up the discovery of new drugs against Huntington’s disease
This application note demonstrates how the HTRF® soluble Mutant and Total HTT immunoassays are suitable for a sensitive and reliable measurement of HTT proteins in cell and brain tissue lysates.
eBook Icon   eBook
Autophagy regulation eBook
Key facts about autophagy and mitophagy; Infographics to apprehend the basics; Cutting-edge knowledge. Download this eBook.
Application Note Icon   Application Note
Quantifying the degradation of RBM39 in Neuroblastoma cells treated with molecular glue degraders using HTRF technology
This application note highlights the use of HTRF immunoassays to evaluate RBM39 degradation in neuroblastoma cancer cells treated with Indilsulam and CeMM1-4 molecular glue degraders.
Flyer Icon   Flyer
Simplify your 16S library prep and analysis.
This flyer provides guidance on which NEXTFLEX metagenomic kit to use for microbial community profiling projects
Whitepaper Icon   Whitepaper
An overview of atherosclerosis
Recent developments in our understanding of atherosclerosis from a molecular perspective include the discovery of new players in disease pathogenesis. Discover more in this white paper!
Application Note Icon   Application Note
Investigate mechanism of action of drugs targeting TDP-43 phosphorylation and aggregation with HTRF-based detection assays
This Application Note Illustrates how to assess phospho-TDP-43 modulation (Ser 409/410) with HTRF assays combined to the Protein Disaggregation kit in aggregated models.
Technical Note Icon   Technical Note
Smart Tray accessories for higher throughput optical imaging on the IVIS Spectrum 2 and IVIS SpectrumCT 2
Using Smart Tray accessories for higher throughput optical imaging on the IVIS Spectrum 2 and IVIS SpectrumCT 2.
eBook Icon   eBook
10 key factors to improve your cell counting results
eBook describing considerations and best practices to help you improvethe quality of your cell counting results.
Technical Note Icon   Technical Note
Key success tips to perform β-arrestin 2 recruitment assays by using the B-arr2 recruitment kit with GPCRs
This technical note provides valuable tips for performing B-arr2 recruitment assays on adherent cell lines overexpressing GPCRs.
Technical Note Icon   Technical Note
How to access true Kd values in Protein-Protein Interaction assays
This technical note draws on different case scenarios and assay formats to demonstrate the usefulness of the Cheng Prusoff equation in predicting PPI inhibitors potency.
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