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NeoBase 2 Non-derivatized MSMS kit

NeoBase™ 2 kit, The next generation in MSMS based newborn screening for detecting more than 30 different metabolic diseases from a single dried blood spot sample using a MSMS tandem mass spectrometer.

Feature Specification
Application Newborn Screening

NeoBase™ 2 kit, The next generation in MSMS based newborn screening for detecting more than 30 different metabolic diseases from a single dried blood spot sample using a MSMS tandem mass spectrometer.

Product Variant
NeoBase™ 2 MSMS kit may not be available in all countries, such as Canada. Please check out availability with your local Revvity representative.
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Overview

The next generation in tandem mass spectrometry based newborn screening, the NeoBase™ 2 Non-derivatized MSMS kit gives you the ability to screen for all the common acid, organic acid and fatty acid oxidation.

  • For more than 50 analytes, including markers for screening of x-ald and ada scid, from a single DBS punch with a single extraction and incubation step.
  • A reformulated flow solvent that improves ionization and makes it easy to switch between the NeoLSD™ kit and NeoBase™ 2 kit
  • DBS quality controls with analyte concentrations adjusted at clinically significant levels
  • All internal standards are in a single vial making reconstitution easy. Extraction solution is stable for up to two weeks, eliminating the need for daily preparation.
  • Shorter extraction time, shorter incubation time and shorter run time
  • New specific markers for urea cycle disorders asa-ld, otcd, cps-i and nags as well as for ADA SCID providing more conclusive screening results

Specifications

Application
Newborn Screening
Brand
NeoBase 2
Detection Modality
Mass Spectrometry (MSMS)
Disorders
Metabolic Disorders
Instrument Compatibility
QSight
Sample Type
Dried blood spots
Technology
Mass Spectrometry
Unit Size
1 kit

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Technical Note
Technical Note NeoBase 2 on Sciex Triple Quad 4500MD - digital

Technical note - Neobase2 on SCIEX triple Quad - digital

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