Discovery and Lead Optimization

From target identification to lead optimization

In the field of cell and gene therapy, identifying genetic targets and optimizing them for therapeutic application is a critical first step. At Revvity, we offer cutting-edge genomic tools and technologies that help accelerate this phase, from target discovery to validation and optimization, ensuring your therapy has the strongest foundation for success.

Discovery steps include:

• Target identification and validation: Our advanced genomic tools, including CRISPR-Cas9 and base editing, provide precise genetic modifications. By leveraging sophisticated screening techniques and gene editing capabilities, we help you uncover the genes responsible for disease pathology. Discover how our CRISPR and base editing tools can fast-track your gene therapy development from target identification to optimization.
• Biological mechanism of action: Understanding how genes interact with biological systems is essential for developing effective therapies. We offer imaging solutions, cell-line engineering, and multimode assays to reveal the underlying mechanisms that drive disease processes. Understand the biology behind disease with our advanced cell-line engineering, multimode detection assays, and high-content imaging solutions.
• Gene editing: With our Pin-point™ base editing platform and viral delivery systems, you can achieve significantly high specificity in gene editing. This supports you in tailoring your therapy with high accuracy and minimal off-target effects. Explore how our advanced gene editing technologies can help overcome barriers and drive the development of safer, more effective therapies.