Unlocking the power of precision: 3D spheroid formation with the FlexDrop Plus

Unlocking the Power of Precision

The pursuit of more accurate and predictive in vitro cancer models has led to a growing interest in 3D cell culture techniques. Among these, spheroid formation offers a promising avenue for mimicking the complex in vivo tumor microenvironment. However, traditional spheroid formation methods often face challenges in terms of scalability, reproducibility, and the uniformity of resulting spheroids.

In this study, we introduce a novel approach utilizing the FlexDrop™ Plus, a cutting-edge noncontact liquid dispensing device. By combining the FlexDrop Plus with the liquid overlay technique (LOT), we aim to address the limitations of existing methods and provide a more efficient and reliable solution for spheroid generation.

The capabilities of the FlexDrop Plus to generate A549 lung cancer spheroids are presented as well as the key advantages of this approach.

Please read this application note to explore the potential of the FlexDrop Plus in spheroid formation.

For research use only. Not for use in diagnostic procedures.