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Gene editing of primary immune cells to aid next-generation cellular immunotherapies

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Our current understanding of the pathways leading to cytokine production in humans originates from studies in transformed T-cell lines, which do not accurately recapitulate primary human cell biology. This whitepaper describes how loss- and gain-of function studies with primary human T cells offer critical insights into the pathways required for cytokine regulation.

For research use only. Not for use in diagnostic procedures.

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Gene editing of primary immune cells to aid next-generation cellular immunotherapies

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