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Application Note

Compound inhibitor profiling using the FlexDrop Plus Non-Contact Dispenser.

The ADP-Glo™ Kinase Assay : a powerful tool for drug discovery

The ADP-Glo™ Kinase Assay is a crucial tool in drug discovery research. It measures the activity of kinases, essential enzymes involved in cellular signaling. By quantifying the amount of ADP produced during kinase reactions, the assay helps identify potential drug candidates that can inhibit kinase activity and treat diseases like cancer and inflammation.

Experimental Overview

The study involved comparing the FlexDrop™ Plus to other liquid handling methods, including a multichannel pipette and a pipetting station. Experiments were conducted using different enzymes and compounds to assess the FlexDrop Plus's performance in various aspects of the ADP-Glo™ Kinase Assay, such as compound dilution, reagent addition, and overall assay execution.

The FlexDrop Plus Non-Contact Dispenser: A Game-Changer

The FlexDrop Plus has the potential to revolutionize the compound inhibitor profiling process. By automating key steps and improving efficiency, it can accelerate drug discovery efforts and reduce costs. This study provides valuable insights into the capabilities of the FlexDrop Plus and its potential to enhance the ADP-Glo™ Kinase Assay.

To learn more about the FlexDrop Plus and its potential to streamline your compound inhibitor profiling workflows, we invite you to explore the complete document and review the detailed results.

For research use only. Not for use in diagnostic procedures.

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Compound inhibitor profiling using the FlexDrop Plus Non-Contact Dispenser.