Skip to main content
Menu
US
ppi-avidity
Application Note

Harness avidity without compromising on pharmacology

Characterize compounds in extra-low affinity interactions

This Note groups protocols and data showing how a Biotin-Streptavidin system can be used to increase the apparent affinity of a protein-protein interaction and make it easy to characterize.

No need to worry about the pharmacology of compounds tested this way: you will also see experiments demonstrating that this avidity-based approach does not impair compound characterization.

Features:

  • Apparent affinity of weak interactions enhanced with the Biot-SA system
  • Evidence for pharmacological validation
  • Kd determination using the avidity approach

For research use only. Not for use in diagnostic procedures.

To view the full content please answer a few questions

By submitting my personal data, I acknowledge that Revvity Inc. and its affiliates (“Company”) will process my personal data provided above consistent with the Company’s Privacy Policy available here.

CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Download Resource

Harness avidity without compromising on pharmacology